DL-Alanine (2,3-13C2)

[Description]:

DL-Alanine-13C2 (DL-2-Aminopropionic acid-13C2) is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

[3]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

[4]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

[5]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

[6]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

[7]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

[8]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

[9]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

[10]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

[11]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.