Murabutide

Names

[ CAS No. ]:
74817-61-1

[ Name ]:
Murabutide

[Synonym ]:
N-acetylmuramyl-alanylglutamine-n-butyl ester

Biological Activity

[Description]:

Murabutide is a safe synthetic immunomodulator. Murabutide can reduce CD4 and CCR5 receptor expression and secrete high levels of beta-chemokines. Murabutide enhances nonspecific resistance against viral infections. Murabutide did not affect virus entry, reverse transcriptase activity or early proviral DNA formation in the cytoplasm of infected cells[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Inflammation/Immunology

[References]

[1]. E C Darcissac, et al. The synthetic immunomodulator murabutide controls human immunodeficiency virus type 1 replication at multiple levels in macrophages and dendritic cells. J Virol. 2000, 74, 17.  

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
950.4ºC at 760 mmHg

[ Molecular Formula ]:
C23H40N4O11

[ Molecular Weight ]:
548.58400

[ Flash Point ]:
528.6ºC

[ Exact Mass ]:
548.26900

[ PSA ]:
235.84000

[ Index of Refraction ]:
1.549

Related Compounds