2,3-dimethyl-4-phenyl-1-[(E)-3-phenylprop-2-enyl]piperidin-4-ol

Names

[ CAS No. ]:
76950-50-0

[ Name ]:
2,3-dimethyl-4-phenyl-1-[(E)-3-phenylprop-2-enyl]piperidin-4-ol

[Synonym ]:
1-Cinnamyl-2,3-dimethyl-4-phenyl-4-hydroxypiperidine
N-Cinnamyl-4-phenyl-5,6-dimethylpiperidin
1-Cinnamyl-2,3-dimethyl-4-phenyl-4-piperidinol
4-Piperidinol,1-cinnamyl-2,3-dimethyl-4-phenyl

Chemical & Physical Properties

[ Density]:
1.059g/cm3

[ Boiling Point ]:
477.7ºC at 760 mmHg

[ Molecular Formula ]:
C22H27NO

[ Molecular Weight ]:
321.45600

[ Flash Point ]:
94.9ºC

[ Exact Mass ]:
321.20900

[ PSA ]:
23.47000

[ LogP ]:
4.25580

[ Index of Refraction ]:
1.587

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN6957200
CHEMICAL NAME :
4-Piperidinol, 1-cinnamyl-2,3-dimethyl-4-phenyl-
CAS REGISTRY NUMBER :
76950-50-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H27-N-O
MOLECULAR WEIGHT :
321.50
WISWESSER LINE NOTATION :
T6NTJ A2U1R& B1 C1 DQ DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - altered sleep time (including change in righting reflex) Behavioral - excitement
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,699,1980

Related Compounds