γ-Sanshool

Names

[ CAS No. ]:
78886-65-4

[ Name ]:
γ-Sanshool

Biological Activity

[Description]:

γ-Sanshool can be isolated from Zanthoxylum piperitum. γ-Sanshool inhibits human ACAT-1 and ACAT-2 activities with IC50s of 12.0 and 82.6 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[Target]

12.0 and 82.6 μM (human ACAT-1 and ACAT-2)[1]


[References]

[1]. Park YD, et al. Human acyl-CoA: cholesterol acyltransferase inhibitory activities of aliphatic acid amides from Zanthoxylum piperitum DC. Biol Pharm Bull. 2007 Jan;30(1):205-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H27NO

[ Molecular Weight ]:
273.41

[ Exact Mass ]:
273.20900

[ PSA ]:
32.59000

[ LogP ]:
5.18000

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream