5-bromo-2,6-dimethyl-4-oxo-N,1-diphenylpyridine-3-carboxamide

Names

[ CAS No. ]:
80357-45-5

[ Name ]:
5-bromo-2,6-dimethyl-4-oxo-N,1-diphenylpyridine-3-carboxamide

[Synonym ]:
1,4-Dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxonicotinamide
5-bromo-1,4-dihydro-2,6-dimethyl-N,1-diphenyl-4-oxo-3-pyridinecarboxamide
Nicotinamide,1,4-dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo
1,4-Dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo-3-pyridinecarboxamide

Chemical & Physical Properties

[ Density]:
1.473g/cm3

[ Boiling Point ]:
535ºC at 760 mmHg

[ Molecular Formula ]:
C20H17BrN2O2

[ Molecular Weight ]:
397.26500

[ Flash Point ]:
277.4ºC

[ Exact Mass ]:
396.04700

[ PSA ]:
54.59000

[ LogP ]:
4.85310

[ Index of Refraction ]:
1.675

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QS4470500
CHEMICAL NAME :
Nicotinamide, 1,4-dihydro-5-bromo-2,6-dimethyl-N,1-diphenyl-4-oxo-
CAS REGISTRY NUMBER :
80357-45-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H17-Br-N2-O2
MOLECULAR WEIGHT :
397.30
WISWESSER LINE NOTATION :
T6N DVJ AR& B1 CVMR& EE F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
562 mg/kg
TOXIC EFFECTS :
Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,131,1982

Synthetic Route


Related Compounds