9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
Names
[ CAS No. ]:
84082-03-1
[ Name ]:
9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
[Synonym ]:
4-demethoxy-6-deoxydaunorubicin
4-Demethoxy-4-iso-propoxy-daunorubicin*HCl
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Boiling Point ]:
739.5ºC at 760 mmHg
[ Molecular Formula ]:
C26H27NO8
[ Molecular Weight ]:
481.49400
[ Flash Point ]:
401ºC
[ Exact Mass ]:
481.17400
[ PSA ]:
156.38000
[ LogP ]:
2.01500
[ Index of Refraction ]:
1.685
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9293220
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hex opyranosyl)oxy)- 7,8,9,10-tetrahydro-6,8-dihydroxy-, (8S-cis)-
- CAS REGISTRY NUMBER :
- 84082-03-1
- LAST UPDATED :
- 198806
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C26-H27-N-O8
- MOLECULAR WEIGHT :
- 481.54
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,5499,1986