3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline
Names
[ CAS No. ]:
84218-38-2
[ Name ]:
3-chloro-N-[[1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]aniline
Chemical & Physical Properties
[ Density]:
1.272g/cm3
[ Boiling Point ]:
665ºC at 760 mmHg
[ Molecular Formula ]:
C27H28ClN3O2
[ Molecular Weight ]:
461.98300
[ Flash Point ]:
356ºC
[ Exact Mass ]:
461.18700
[ PSA ]:
49.52000
[ LogP ]:
6.06090
[ Index of Refraction ]:
1.669
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NX4919200
- CHEMICAL NAME :
- Isoquinoline, 1,2,3,4-tetrahydro-2-((m-chloroanilino)methyl)-6,7-di methoxy-1- (3-indolylmethyl)-
- CAS REGISTRY NUMBER :
- 84218-38-2
- LAST UPDATED :
- 198609
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C27-H28-Cl-N3-O2
- MOLECULAR WEIGHT :
- 462.03
- WISWESSER LINE NOTATION :
- T66 CNT&J C1MR CG& HO1 IO1 B1- DT56 BMJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - proteases Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,1233,1982