107019-95-4

107019-95-4 structure

Name: Hymenidin
Chemical Name: 2-debromooroidin
CAS Number: 107019-95-4
Molecular Formula: C₁₁H₁₂BrN₅O
Molecular Weight: 310.15000
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2016-01-15 17:47:27
Modify Date: 2024-01-03 00:00:07
Hymenidin is a natural antagonist of serotonergic receptor and inhibitor of voltage-gated potassium channels. Hymenidin also induces cancer cell apoptosis[1][2][3].

Name	2-debromooroidin
Synonyms	hymenidin

Description	Hymenidin is a natural antagonist of serotonergic receptor and inhibitor of voltage-gated potassium channels. Hymenidin also induces cancer cell apoptosis[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Kobayashi J, et al. A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp. Experientia. 1986 Oct 15;42(10):1176-7. [2]. Zidar N, et al. Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. Eur J Med Chem. 2017 Oct 20;139:232-241. [3]. Tihomir Tomašič, et al. Analogues of the marine alkaloids oroidin, clathrodin, and hymenidin induce apoptosis in human HepG2 and THP-1 cancer cells. MedChemComm. 2015, 6(1): 105-110.