127512-29-2

127512-29-2 structure

Name: 18:1 DAP
Chemical Name: 1,2-Dioleoyloxy-3-(dimethylamino)propane
CAS Number: 127512-29-2
Molecular Formula: C₄₁H₇₇NO₄
Molecular Weight: 648.05400
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-05-17 15:06:07
Modify Date: 2024-01-05 11:45:10
DODAP is a cationic lipid. The ionizable lipid DODAP is a lipid component of the liposome. DODAP can be used to encapsulate siRNA, immunostimulatory chemotherapeutic agents for in vitro and in vivo delivery and so on[1][2][3].

Name	1,2-Dioleoyloxy-3-(dimethylamino)propane
Synonyms	[3-(dimethylamino)-2-octadec-9-enoyloxypropyl] octadec-9-enoate

Description	DODAP is a cationic lipid. The ionizable lipid DODAP is a lipid component of the liposome. DODAP can be used to encapsulate siRNA, immunostimulatory chemotherapeutic agents for in vitro and in vivo delivery and so on[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Dabbas S, et al. Importance of the liposomal cationic lipid content and type in tumor vascular targeting: physicochemical characterization and in vitro studies using human primary and transformed endothelial cells. Endothelium. 2008;15(4):189-201. [2]. Hamzah J, et al. Targeted liposomal delivery of TLR9 ligands activates spontaneous antitumor immunity in an autochthonous cancer model. J Immunol. 2009;183(2):1091-1098. [3]. Liu Q, et al. Biotinylated cyclen-contained cationic lipids as non-viral gene delivery vectors. Chem Biol Drug Des. 2013;82(4):376-383.

Hazard Codes	Xi

Precursor 3
112-77-6 623-57-4 112-80-1
DownStream 0