Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Picraline
Price:
Purity: 96.5%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: Picraline
Price: ￥4150.0/5mg
Purity: 96.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

2671-32-1

2671-32-1 structure

2671-32-1 structure

Name: picraline
Chemical Name: 2-(Cyanomethyl)-1-propene-1,1,3,3-tetracarbonitrile
CAS Number: 2671-32-1
Molecular Formula: C₂₃H₂₆N₂O₅
Molecular Weight: 410.46
Catalog: Natural product Alkaloid
Create Date: 2016-10-05 23:36:40
Modify Date: 2024-01-10 17:38:03
Picraline is a natural alkaloid that targets opioid receptors with binding affinities with Ki values of 132 μM, 2.38 μM and 98.8 μM for μOR, κOR and δOR, respectively[1].

Name	2-(Cyanomethyl)-1-propene-1,1,3,3-tetracarbonitrile
Synonyms	2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 14-[(acetyloxy)methyl]-3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aS,12aR,12bS)- Methyl (2α,5α,15α,19E)-16-(acetoxymethyl)-1,2-dihydro-2,5-epoxyakuammilan-17-oate

Description	Picraline is a natural alkaloid that targets opioid receptors with binding affinities with Ki values of 132 μM, 2.38 μM and 98.8 μM for μOR, κOR and δOR, respectively[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	μ Opioid Receptor/MOR:132 μM (Ki) κ Opioid Receptor/KOR:2.38 μM (Ki) δ Opioid Receptor/DOR:98.8 μM (Ki)
References	[1]. Simone M Creed, et al. Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids. J Nat Prod. 2021 Jan 22;84(1):71-80.

Density	1.4±0.1 g/cm3
Boiling Point	548.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₆N₂O₅
Molecular Weight	410.46
Flash Point	285.2±30.1 °C
Exact Mass	410.184174
PSA	77.10000
LogP	2.84
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.650

Hazard Codes	Xi