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630421-48-6

630421-48-6 structure
630421-48-6 structure

Name 2-Methyl-2-propanyl {(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2 -vinylcyclopropyl}carbamate
Synonyms (3S)-N-BOC-3-fluoropyrrolidine
(3S)-3-fluoropyrrolidine-1-carboxylic acid tert-butyl ester
tert-butyI (3S)-3-fluoropyrrolidine-1-carboxylate
N-trans-BOC-(3S)-Fluoropyrrolidine
t-butyl (1R,2S)-1-(cyclopropylsulfonyl-carbamoyl)-2-vinylcyclopropylcarbamate
(S)-tert-butyl 3-fluoropyrrolidine-1-carboxylate
cyclopropanesulfonic acid (1-(R)-tert-butoxycarbonylamino-2-(S)-vinylcyclopropanecarbonyl)-amide
tert-butyl ((1R,2S)-1-{[(cyclopropylsulfonyl)amino]carbonyl}-2-vinylcyclopropyl)carbamate
(S)-1-Boc-3-fluoropyrrolidine
tert-butyl ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)carbamate
Density 1.299g/cm3
Molecular Formula C14H22N2O5S
Molecular Weight 330.40000
Exact Mass 330.12500
PSA 116.93000
LogP 3.18970
Index of Refraction 1.547
Storage condition 2-8°C

~98%

630421-48-6 structure

630421-48-6

Literature: Scola, Paul M.; Wang, Alan Xiangdong; Good, Andrew C.; Sun, Li-Qiang; Combrink, Keith D.; Campbell, Jeffrey A.; Chen, Jie; Tu, Yong; Sin, Ny; Venables, Brian L.; Sit, Sing-Yuen; Chen, Yan; Cocuzza, Anthony; Bilder, Donna M.; D'Andrea, Stanley; Zheng, Barbara; Hewawasam, Piyasena; Ding, Min; Thuring, Jan; Li, Jianqing; Hernandez, Dennis; Yu, Fei; Falk, Paul; Zhai, Guangzhi; Sheaffer, Amy K.; Chen, Chaoqun; Lee, Min S.; Barry, Diana; Knipe, Jay O.; Li, Wenying; Han, Yong-Hae; Jenkins, Susan; Gesenberg, Christoph; Gao, Qi; Sinz, Michael W.; Santone, Kenneth S.; Zvyaga, Tatyana; Rajamani, Ramkumar; Klei, Herbert E.; Colonno, Richard J.; Grasela, Dennis M.; Hughes, Eric; Chien, Caly; Adams, Stephen; Levesque, Paul C.; Li, Danshi; Zhu, Jialong; Meanwell, Nicholas A.; McPhee, Fiona Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 1708 - 1729

~92%

630421-48-6 structure

630421-48-6

Literature: Bristol-Myers Squibb Company Patent: US2008/14173 A1, 2008 ; Location in patent: Page/Page column 34 ; US 20080014173 A1

~90%

630421-48-6 structure

630421-48-6

Literature: BRISTOL-MYERS SQUIBB COMPANY Patent: WO2008/64057 A1, 2008 ; Location in patent: Page/Page column 63 ;

~%

630421-48-6 structure

630421-48-6

Literature: TaiGen Biotechnology Co., Ltd. Patent: US2011/65737 A1, 2011 ; US 20110065737 A1 Title/Abstract Full Text Show Details TAIGEN BIOTECHNOLOGY CO., LTD.; LIU, Chen-Fu; LEE, Kuang-Yuan; CHENG, Pei-Chin; LIU, Yo-Chin; LO, Pin; TSENG, Kuo-Feng; CHEN, Chih-Ming; KING, Chi-Hsin Richard; LIN, Chu-Chung Patent: WO2011/34518 A1, 2011 ; WO 2011/034518 A1

~87%

630421-48-6 structure

630421-48-6

Literature: Idenix Pharmaceuticals, Inc. Patent: US2009/202480 A1, 2009 ; US 20090202480 A1
Precursor  3

DownStream  0