77642-19-4

77642-19-4 structure

77642-19-4 structure

Name: Cyclopent[i]azacyclononadecine-7,17(8H,19H)-dione,9,10,13,14,15,16,20,20a-octahydro-15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-,(1Z,3E,5E,9S,11E,15S,19S,20aR)-
Chemical Name: hitachimycin
CAS Number: 77642-19-4
Molecular Formula: C₂₉H₃₅NO₅
Molecular Weight: 477.59200
Create Date: 2016-10-31 15:09:17
Modify Date: 2024-01-09 20:03:10

Name	hitachimycin
Synonyms	Antibiotic KG-2245 KG-2245 KM-4927 Antibiotic KM-4927 stubomycin

Molecular Formula	C₂₉H₃₅NO₅
Molecular Weight	477.59200
Exact Mass	477.25200
PSA	95.86000
LogP	5.13860

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY5946700

CHEMICAL NAME :: Cyclopent(i)azacyclononadecine-7,17(8H,19H)-dione, 9,10,13,14,15,16,20,20a-octahydro- 15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-

CAS REGISTRY NUMBER :: 77642-19-4

LAST UPDATED :: 199206

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C29-H35-N-O5

MOLECULAR WEIGHT :: 477.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human HeLa cell

DOSE/DURATION :: 2500 ug/L

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,259,1981

Precursor 4
124944-58-7 124944-54-3 124944-56-5 52813-63-5
DownStream 0