80483-89-2

80483-89-2 structure

Name: Isohomobrassinolide
Chemical Name: (2R,3S,22S,24S)-2,3,22,23-TETRAHYDROXY-24-ETHYL-β-HOMO-7-OXA-5A-CHOLESTAN-6-ONE
CAS Number: 80483-89-2
Molecular Formula: C₂₉H₅₀O₆
Molecular Weight: 494.704
Catalog: Chemical pesticide Plant Growth Regulator
Create Date: 2018-04-11 08:00:00
Modify Date: 2024-01-02 16:51:45
(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active[1].

Name	(2R,3S,22S,24S)-2,3,22,23-TETRAHYDROXY-24-ETHYL-β-HOMO-7-OXA-5A-CHOLESTAN-6-ONE
Synonyms	Cholest-5-ene-3\|A,22-diol 22R-hydroxycholesterol (22R)-22-hydroxycholesterol cholest-5-en-3beta,22-diol 22S,23S-28-homobrassinolide 22S,23S-homobrassinolide 22(S)-hydroxycholesterol 3H-Benz[c]indeno[5,4-e]oxepin-3-one, 10-[(1S,2S,3S,4S)-4-ethyl-2,3-dihydroxy-1,5-dimethylhexyl]hexadecahydro-5,6-dihydroxy-7a,9a-dimethyl-, (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)- Cholest-5-ene-3beta,22-diol (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3S,4S,5S)-5-Ethyl-3,4-dihydroxy-6-methyl-2-heptanyl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one 22-Hydroxycholesterol (22S)-22-Hydroxycholesterol Isohomobrassinolide

Description	(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	(22S,23S)-Homobrassinolide slightly stimulates ferricyanide reduction and promotes uptake of sucrose and alpha-aminoisobutyric acid [2].
References	[1]. Esposito D, et al. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J Med Chem. 2011;54(12):4057-4066. [2]. Dahse I, et al. Effects of (22S,23S)-Homobrassinolide and Related Compounds on Membrane Potential and Transport of Egeria Leaf Cells. Plant Physiol. 1990;93(3):1268-1271.

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WGK Germany	3