197142-36-2

197142-36-2 structure

Name: (1S,3S,5S)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Chemical Name: (3S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
CAS Number: 197142-36-2
Molecular Formula: C₁₁H₁₇NO₄
Molecular Weight: 227.25700
Create Date: 2016-07-16 14:01:03
Modify Date: 2024-01-08 16:09:27

Name	(3S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid
Synonyms	(4S,5S)-metano-N-Boc-L-proline s-BOC-4,5-methanoproline (1S,3S,5S)-2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester N-Boc-L-cis-4,5-methanoproline (1S,3S,5S)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid

Boiling Point	355.9±25.0 °C at 760 mmHg (lit.)
Molecular Formula	C₁₁H₁₇NO₄
Molecular Weight	227.25700
Exact Mass	227.11600
PSA	66.84000
LogP	1.40680

Hazard Codes	Xi

214193-11-0

~97%

197142-36-2

Literature: ALANTOS PHARMACEUTICALS, INC. Patent: WO2006/116157 A2, 2006 ; Location in patent: Page/Page column 114-115 ; WO 2006/116157 A2

1313751-21-1

~99%

197142-36-2

Literature: BRISTOL-MYERS SQUIBB COMPANY; LOPEZ, Omar D.; ST. LAURENT, Denis R.; GOODRICH, Jason; ROMINE, Jeffrey Lee; SERRANO-WU, Michael; YANG, Fukang; KAKARLA, Ramesh; YANG, Xuejie; QIU, Yuping; SNYDER, Lawrence B. Patent: WO2011/82077 A1, 2011 ; Location in patent: Page/Page column 299 ;

7647-01-0

~82%

197142-36-2

Literature: BRISTOL-MYERS SQUIBB COMPANY Patent: WO2004/52850 A2, 2004 ; Location in patent: Page 77 ; WO 2004/052850 A2

138629-30-8

197142-36-2

Literature: Hanessian, Stephen; Reinhold, Ulrich; Gentile, Gabriella Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 17 p. 1881 - 1884

361440-67-7

197142-36-2

Precursor 4
214193-11-0 7647-01-0 138629-30-8 361440-67-7
DownStream 1
361440-67-7

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2137576-06-6	2229636-75-1
6906-52-1	930439-75-1