CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UV8113000
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CHEMICAL NAME :
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Pyrimidine, 2-(N-(1-(5-chloro-2-methoxybenzyl)-4-piperidyl)methyl amino)-, dihydrochloride
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CAS REGISTRY NUMBER :
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76167-81-2
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LAST UPDATED :
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199112
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C18-H23-Cl-N4-O.2Cl-H
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MOLECULAR WEIGHT :
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419.82
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WISWESSER LINE NOTATION :
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T6N CNJ BN1&- DT6NTJ A1R CG FO1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>300 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - relaxation (isolated tissues)
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REFERENCE :
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FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>100 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - relaxation (isolated tissues)
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REFERENCE :
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FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980
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