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63284-71-9

63284-71-9 structure
63284-71-9 structure

Name nuarimol
Synonyms Gauntlet
UNII:ZU7K80U0CY
murox
Caswell No. 419G
trimifruitsc
triminol
el2289
Trimiol
Nuarimol
α-(2-Chlorophenyl)-α-(4-fluorophenyl)-5-pyrimidinemethanol
(2-chlorophenyl)(4-fluorophenyl)pyrimidin-5-ylmethanol
el228
(2-Chlorphenyl)(4-fluorphenyl)pyrimidin-5-ylmethanol
(RS)-2-chloro-4’-fluoro-α-(pyrimidin-5-yl)benzhydryl alcohol
(2-Chlorophenyl)(4-fluorophenyl)5-pyrimidinylmethanol
a-(2-Chlorophenyl)-a-(4-fluorophenyl)-5-pyrimidinemethanol
MFCD00078677
(RS)-2-Chloro-4'-fluoro-a-(pyrimidin-5-yl)benzhydryl alcohol
rac-(R)-(2-chlorophenyl)(4-fluorophenyl)(pyrimidin-5-yl)methanol
(±)-Nuarimol
TRIMIDAL
guantlet
EINECS 264-071-1
5-Pyrimidinemethanol, α-(2-chlorophenyl)-α-(4-fluorophenyl)-
Density 1.4±0.1 g/cm3
Boiling Point 475.2±40.0 °C at 760 mmHg
Melting Point 126°C
Molecular Formula C17H12ClFN2O
Molecular Weight 314.741
Flash Point 241.2±27.3 °C
Exact Mass 314.062225
PSA 46.01000
LogP 2.68
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.623

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV9279700
CHEMICAL NAME :
5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-fluorophenyl)-
CAS REGISTRY NUMBER :
63284-71-9
LAST UPDATED :
199806
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C17-H12-Cl-F-N2-O
MOLECULAR WEIGHT :
314.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,625,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,625,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,625,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,625,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,625,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - domestic
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A303,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
312 mg/kg/5D-I
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), zonal Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
REFERENCE :
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 14,337,1994
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8736 mg/kg/2Y-C
TOXIC EFFECTS :
Liver - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545244
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22-36
Safety Phrases S26
RIDADR NONH for all modes of transport
RTECS UV9279700
Precursor  0

DownStream  1