69981-39-1

69981-39-1 structure

Name: Bis-Tos-(2-hydroxyethyl disulfide)
Chemical Name: bis(toluolsulfonate)-(2-hydroxyethyl)-disulfide
CAS Number: 69981-39-1
Molecular Formula: C₁₈H₂₂O₆S₄
Molecular Weight: 462.62400
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-04-01 14:10:46
Modify Date: 2024-01-10 00:17:29
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	bis(toluolsulfonate)-(2-hydroxyethyl)-disulfide

Description	Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.