1356962-34-9

1356962-34-9 structure

Name: HG-14-10-04
Chemical Name: 5-Chloro-4-(1H-indol-3-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidin-2-amine
CAS Number: 1356962-34-9
Molecular Formula: C₂₉H₃₄ClN₇O
Molecular Weight: 532.08000
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2018-05-27 16:27:52
Modify Date: 2024-01-02 10:57:59
HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.

Name	5-Chloro-4-(1H-indol-3-yl)-N-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidin-2-amine
Synonyms	HG-14-10-04

Description	HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK Research Areas >> Cancer
References	[1]. U.S. Pat. Appl. Publ. (2012), US 20120028924 A1