503860-57-9

503860-57-9 structure

Name: SAR502250
Chemical Name: uda-680
CAS Number: 503860-57-9
Molecular Formula: C₁₉H₁₈FN₅O₂
Molecular Weight: 367.37700
Create Date: 2018-04-30 05:27:21
Modify Date: 2024-01-19 19:01:20
SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD).

Name	uda-680
Synonyms	2-[(2S)-2-(2-(4-fluorophenyl)morpholin-4-yl)]-1-methyl-1H-[4,4']bipyrimidinyl-6-one