1370290-34-8

1370290-34-8 structure

Name: LDHA-IN-4
Chemical Name: {4-[4-({3-[(2-Methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl}amino)-4-oxobutyl]benzyl}malonic acid
CAS Number: 1370290-34-8
Molecular Formula: C₂₅H₂₇N₃O₆S
Molecular Weight: 497.563
Catalog: Signaling Pathways Metabolic Enzyme/Protease Lactate Dehydrogenase
Create Date: 2018-04-20 21:23:55
Modify Date: 2024-02-05 14:37:43
AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1].

Name	{4-[4-({3-[(2-Methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl}amino)-4-oxobutyl]benzyl}malonic acid
Synonyms	Propanedioic acid, 2-[[4-[4-[[3-[(2-methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]- {4-[4-({3-[(2-Methyl-1,3-benzothiazol-6-yl)amino]-3-oxopropyl}amino)-4-oxobutyl]benzyl}malonic acid AZ-33

Description	AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
References	[1]. Ward RA,et al. Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306.