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  • DC Chemicals Limited
  • China
  • Product Name: MTDIA
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1399840-35-7

1399840-35-7 structure
1399840-35-7 structure
  • Name: MTDIA
  • Chemical Name: MT-DADMe-ImmA
  • CAS Number: 1399840-35-7
  • Molecular Formula:
  • Molecular Weight:
  • Create Date: 2018-05-03 15:34:02
  • Modify Date: 2024-07-18 13:20:52
  • MTDIA, also known as MT-DADMe-ImmA, and Methylthio-DADMe-Immucillin A, is a MTAP inhibitor. Human 5'-methylthioadenosine phosphorylase (MTAP) is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer candidates. TS analogues of MTAP incorporate a cationic nitrogen and a protonated 9-deazaadenine leaving group, which are mimics of the ribocation transition state. MT-ImmA and MT-DADMe-ImmA are two examples of these TS analogues.

Name MT-DADMe-ImmA
Synonyms MTDIA HCl
No Any Chemical & Physical Properties