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142937-50-6

142937-50-6 structure
142937-50-6 structure
  • Name: Triptoquinone B
  • Chemical Name: Triptoquinone B
  • CAS Number: 142937-50-6
  • Molecular Formula: C20H26O4
  • Molecular Weight: 330.418
  • Catalog: Natural product Moss
  • Create Date: 2016-04-23 18:12:52
  • Modify Date: 2024-09-11 15:10:50
  • Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].

Name Triptoquinone B
Synonyms 1,4,7(4bH)-Phenanthrenetrione, 5,6,8,8a,9,10-hexahydro-8-(hydroxymethyl)-4b,8-dimethyl-2-(1-methylethyl)-, (4bS,8S,8aR)-
19-Hydroxyabieta-8,12-diene-3,11,14-trione
Triptoquinone B
Description Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].
Related Catalog
Target

IL-1

References

[1]. Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33(47): 7177-7180.

[2]. Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7(5):755-9.

Density 1.2±0.1 g/cm3
Boiling Point 475.4±45.0 °C at 760 mmHg
Molecular Formula C20H26O4
Molecular Weight 330.418
Flash Point 255.4±25.2 °C
Exact Mass 330.183105
PSA 71.44000
LogP 2.77
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.558
Hazard Codes Xi