492-12-6

492-12-6 structure

Name: Plathymenin
Chemical Name: (2S)-2-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-2,3-dihydro-4H-chromen-4-one
CAS Number: 492-12-6
Molecular Formula: C₁₅H₁₂O₆
Molecular Weight: 288.25
Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
Create Date: 2018-07-13 22:12:47
Modify Date: 2024-01-22 11:41:56
Plathymenin is a flavonoid that can be isolated from Nepalese propolis. Plathymenin is a potent inhibitor of 5-LOX[1][2].

Name	(2S)-2-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-2,3-dihydro-4H-chromen-4-one
Synonyms	4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-6,7-dihydroxy-, (2S)- (2S)-2-(3,4-Dihydroxyphenyl)-6,7-dihydroxy-2,3-dihydro-4H-chromen-4-one

Description	Plathymenin is a flavonoid that can be isolated from Nepalese propolis. Plathymenin is a potent inhibitor of 5-LOX[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase
References	[1]. Funakoshi-Tago M, et al. Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway. Int Immunopharmacol. 2015 Mar;25(1):189-98. [2]. Jiang S, et al. Combined Autodock and comparative molecular field analysis study on predicting 5-lipoxygenase inhibitory activity of flavonoids isolated from Spatholobus suberectus Dunn. Z Naturforsch C J Biosci. 2015;70(3-4):103-13.