1036204-61-1

1036204-61-1 structure

Name: Propargyl-PEG12-OH
Chemical Name: Propargyl-PEG13-alcohol
CAS Number: 1036204-61-1
Molecular Formula: C₂₇H₅₂O₁₃
Molecular Weight: 584.694
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-01-14 16:34:19
Modify Date: 2024-01-22 21:21:10
Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	Propargyl-PEG13-alcohol
Synonyms	3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yn-1-ol MFCD28334508

Description	Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Sandanaraj BS, et al. Rational Design of Supramolecular Dynamic Protein Assemblies by Using a Micelle-AssistedActivity-Based Protein-Labeling Technology. Chemistry. 2018 Oct 26;24(60):16085-16096.