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1365655-92-0

1365655-92-0 structure
1365655-92-0 structure
  • Name: DNP-PEG3-DNP
  • Chemical Name: DNP-PEG3-DNP
  • CAS Number: 1365655-92-0
  • Molecular Formula: C20H24N6O11
  • Molecular Weight: 524.438
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-22 06:44:23
  • Modify Date: 2024-03-10 16:36:35
  • DNP-PEG3-DNP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DNP-PEG3-DNP
Synonyms N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis(2,4-dinitroaniline)
Benzenamine, N,N'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[2,4-dinitro-
MFCD22056318
Description DNP-PEG3-DNP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.5±0.1 g/cm3
Boiling Point 735.3±60.0 °C at 760 mmHg
Molecular Formula C20H24N6O11
Molecular Weight 524.438
Flash Point 398.5±32.9 °C
Exact Mass 524.150330
LogP 3.68
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.647