1416270-18-2
1416270-18-2 structure
- Name: Mutant IDH1-IN-4
- Chemical Name: (R)-8-cyclopropyl-6-(3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile
- CAS Number: 1416270-18-2
- Molecular Formula: C25H34N4O3
- Molecular Weight: 438.56246
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
- Create Date: 2018-06-21 20:15:06
- Modify Date: 2024-02-06 13:20:00
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Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1].
| Name | (R)-8-cyclopropyl-6-(3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile |
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| Description | Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1]. |
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| Related Catalog | |
| Target |
IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1]. |
| References |
[1]. US20170210749A1. |
| Molecular Formula | C25H34N4O3 |
|---|---|
| Molecular Weight | 438.56246 |