187100-75-0

187100-75-0 structure

Name: Myristoyl coenzyme A lithium salt
Chemical Name: MYRISTOYL COENZYME A C14:0 LITHIUM SALT
CAS Number: 187100-75-0
Molecular Formula: C₃₅H₅₈Li₄N₇O₁₇P₃S
Molecular Weight: 1001.62
Catalog: Research Areas Cancer
Create Date: 2018-12-03 12:10:49
Modify Date: 2024-01-13 18:00:56
Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms.

Name	MYRISTOYL COENZYME A C14:0 LITHIUM SALT

Description	Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms.
Related Catalog	Research Areas >> Cancer Research Areas >> Infection
Target	Human Endogenous Metabolite
References	[1]. Raju RV, et al. Coenzyme A dependent myristoylation and demyristoylation in the regulation of bovine spleen N-myristoyltransferase. Mol Cell Biochem. 1996 May 24;158(2):107-13.

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