69297-40-1

69297-40-1 structure

Name: 3-O-cis-p-Coumaroylmaslinic acid
Chemical Name: 3-beta-O-(cis-p-Coumaroyl)maslinic acid
CAS Number: 69297-40-1
Molecular Formula: C₃₉H₅₄O₆
Molecular Weight: 618.843
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2019-01-07 17:53:09
Modify Date: 2024-04-02 11:52:27
3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].

Name	3-beta-O-(cis-p-Coumaroyl)maslinic acid
Synonyms	Olean-12-en-28-oic acid, 2-hydroxy-3-[[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-, (2α,3β)- (2α,3β)-2-Hydroxy-3-{[(2Z)-3-(4-hydroxyphenyl)-2-propenoyl]oxy}olean-12-en-28-oic acid

Description	3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Infection Research Areas >> Metabolic Disease Signaling Pathways >> Anti-infection >> Bacterial
Target	0.46 μM (PTP1B)[1]
References	[1]. de Cássia Lemos Lima R, et al. High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules. 2018;23(7):1755. [2]. Braca A, et al. Antimicrobial triterpenoids from Licania heteromorpha. Planta Med. 2000;66(8):768-769.