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125562-30-3

125562-30-3 structure
125562-30-3 structure
  • Name: Methyl-PEG9-bromide
  • Chemical Name: m-PEG9-bromide
  • CAS Number: 125562-30-3
  • Molecular Formula: C19H39BrO9
  • Molecular Weight: 491.412
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-03 10:17:52
  • Modify Date: 2024-01-09 19:44:23
  • m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG9-bromide
Synonyms 28-Bromo-2,5,8,11,14,17,20,23,26-nonaoxaoctacosane
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane, 28-bromo-
MFCD28950767
Description m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.2±0.0 g/cm3
Boiling Point 498.1±0.0 °C at 760 mmHg
Molecular Formula C19H39BrO9
Molecular Weight 491.412
Flash Point 208.4±0.0 °C
Exact Mass 490.177734
LogP -0.88
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.462