131857-33-5

131857-33-5 structure

Name	CefepiMe-D8 Sulfate
Synonyms	(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[1-methyl(2H8)-1-pyrrolidiniumyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate (1:1)

Description	Cefepime-d8 (sulfate) is the deuterium labeled Cefepime sulfate[1].
Related Catalog	Research Areas >> Others
In Vitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-238.