670270-31-2

670270-31-2 structure

Name: IU1-47
Chemical Name: IU1-47
CAS Number: 670270-31-2
Molecular Formula: C₁₉H₂₃ClN₂O
Molecular Weight: 330.85
Catalog: Signaling Pathways Cell Cycle/DNA Damage Deubiquitinase
Create Date: 2019-06-30 17:37:15
Modify Date: 2024-04-01 20:11:17
IU1-47 is a potent USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 induces tau elimination in cultured neurons[1].

Name	IU1-47

Description	IU1-47 is a potent USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 induces tau elimination in cultured neurons[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase Research Areas >> Neurological Disease
References	[1]. Boselli M, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 Nov 24;292(47):19209-19225.