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  • DC Chemicals Limited
  • China
  • Product Name: TH-34
  • Price: $450.0/100mg $700.0/250mg $1500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

2196203-96-8

2196203-96-8 structure
2196203-96-8 structure
  • Name: TH34
  • Chemical Name: TH34
  • CAS Number: 2196203-96-8
  • Molecular Formula: C15H16N2O2
  • Molecular Weight: 256.30
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
  • Create Date: 2019-06-30 09:26:15
  • Modify Date: 2024-01-02 12:29:24
  • TH34, an HDAC6/8/10 inhibitor with IC50s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3[1].

Name TH34
Description TH34, an HDAC6/8/10 inhibitor with IC50s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3[1].
Related Catalog
Target

HDAC6:4.6 μM (IC50)

HDAC8:1.9 μM (IC50)

HDAC10:7.7 μM (IC50)

In Vitro TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells[1].
References

[1]. Kolbinger FR, et al. The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines. Arch Toxicol. 2018 Aug;92(8):2649-2664.

Molecular Formula C15H16N2O2
Molecular Weight 256.30
Storage condition 2-8℃