Name | FPR Agonist 43 |
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Description | FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2]. |
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Related Catalog | |
Target |
FPR1, FPR2/ALX[1] |
In Vitro | FPR Agonist 43 (10-5-107 nM) is actively potent in the cAMP assay in FPR2/ALX over-expressing CHO cells[1]. FPR Agonist 43 is also active in the GTPγ binding assay (IC50=207±51 nM)[1]. FPR1 is the preferred receptor for FPR Agonist 43 in in both human neutrophils and possibly also in mouse cells[2]. Cell Viability Assay[1] Cell Line: Chinese hamster ovary (CHO) over-expressing human FPR2/ALX receptors Concentration: 10-5, 10-3, 0.1, 10, 1000, 105, 107 nM Incubation Time: Result: Actively potent in the cAMP assay in FPR2/ALX over-expressing CHO cells (IC50 =11.6±1.9 nM). |
References |
Molecular Formula | C20H21ClN4O2 |
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Molecular Weight | 384.86 |
Storage condition | 2-8℃ |