220518-50-3

220518-50-3 structure

220518-50-3 structure

Name: FIM-1
Chemical Name: FIM-1
CAS Number: 220518-50-3
Molecular Formula: C₄₅H₃₂N₄O₈
Molecular Weight: 756.758
Catalog: Signaling Pathways Epigenetics PKC
Create Date: 2019-09-10 10:43:48
Modify Date: 2024-01-20 11:07:31
FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor[1].

Name	FIM-1
Synonyms	3',6'-Dihydroxy-N-(3-{3-[4-(1-methyl-1H-indol-2-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxamide Fim-1 N-[3-(3-[2,5-DIHYDRO-4-(1-METHYL-1H-INDOL-3-YL)-2,5-DIOXO-1H-PYRROL-3-YL]-1H-INDOL-1-YL)PROPYL]-3',6'-DIHYDROXY-3-OXOSPIRO[ISOBENZOFURAN-1[3H],9'-[9H]XANTHENE]-5-CARBOXAMIDE Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide, N-[3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-2-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl]-3',6'-dihydroxy-3-oxo- MFCD03453075

Description	FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Others Signaling Pathways >> TGF-beta/Smad >> PKC
References	[1]. Chen CS, et al. New fluorescent probes for protein kinase C. Synthesis, characterization, and application. J Biol Chem. 1993 Jul 25;268(21):15812-22.

Density	1.5±0.1 g/cm3
Molecular Formula	C₄₅H₃₂N₄O₈
Molecular Weight	756.758
Exact Mass	756.221985
LogP	5.84
Index of Refraction	1.761
Storage condition	Store at -20° C
Water Solubility	Soluble in DMSO or DMF.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport