1531586-64-7
1531586-64-7 structure
- Name: AD-35 phosphate
- Chemical Name: AD-35 phosphate
- CAS Number: 1531586-64-7
- Molecular Formula: C24H27N3O3.H3O4P
- Molecular Weight: 503.485
- Create Date: 2020-01-12 18:03:22
- Modify Date: 2024-04-02 17:53:29
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A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.
| Name | AD-35 phosphate |
|---|
| Description | A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active. |
|---|---|
| References | References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE) |
| Molecular Formula | C24H27N3O3.H3O4P |
|---|---|
| Molecular Weight | 503.485 |