1220476-13-0

1220476-13-0 structure

Name: CSIC E379
Chemical Name: CSIC E379
CAS Number: 1220476-13-0
Molecular Formula: C₂₀H₂₄O
Molecular Weight: 280.411
Create Date: 2020-01-11 17:54:49
Modify Date: 2024-09-14 09:29:28
CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide.

Name	CSIC E379

Description	CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide.
References	References 1. Rial E, et al. Chem Biol. 2011 Feb 25;18(2):264-74. View Related Products by Target Other Targets

Molecular Formula	C₂₀H₂₄O
Molecular Weight	280.411