1301708-12-2

1301708-12-2 structure

Name: BMVC-8C3O
Chemical Name: BMVC-8C3O
CAS Number: 1301708-12-2
Molecular Formula: C₄₂H₅₃I₃N₄O₃
Molecular Weight: 1042.61
Catalog: Research Areas Others
Create Date: 2020-01-23 11:08:51
Modify Date: 2024-01-15 17:44:04
BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s[1].

Name	BMVC-8C3O

Description	BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	BMVC-8C3O induces topological conversion of Tel23 from a hybrid-I G4 to a parallel G4 in K+solution[1]. BMVC-8C3O binding can induce topological changes of different non-parallel human telomeric G4s into the same parallel topology[1].
References	[1]. Wang ZF, et al. A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68.