Name | α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase |
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Synonyms |
EC 2.4.1.145
N-acetylglucosaminyltransferase IV N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV β-acetylglucosaminyltransferase IV uridine diphosphoacetylglucosamine-glycopeptide β4-acetylglucosaminyltransferase IV α-1,3-mannosylglycoprotein β-1,4-N-acetylglucosaminyltransferase GnTIV |
Description | R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor (click here for diagram). The best acceptor for this enzyme is probably the same as that favoured by EC 2.4.1.144, β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase. Reaction: UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-β-D-glucosaminyl]-α-D-mannosyl)-β-D-mannosyl-R = UDP + 3-(2,4-bis[N-acetyl-β-D-glucosaminyl]-α-D-mannosyl)-β-D-mannosyl-R |
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No Any Chemical & Physical Properties |