2112737-25-2

2112737-25-2 structure

Name: Propargyl-PEG10-amine
Chemical Name: Propargyl-PEG10-amine
CAS Number: 2112737-25-2
Molecular Formula: C₂₃H₄₅NO₁₀
Molecular Weight: 495.60
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 09:04:03
Modify Date: 2024-01-07 15:24:28
Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	Propargyl-PEG10-amine

Description	Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.