2112737-25-2
2112737-25-2 structure
- Name: Propargyl-PEG10-amine
- Chemical Name: Propargyl-PEG10-amine
- CAS Number: 2112737-25-2
- Molecular Formula: C23H45NO10
- Molecular Weight: 495.60
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2020-04-13 09:04:03
- Modify Date: 2024-01-07 15:24:28
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Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | Propargyl-PEG10-amine |
|---|
| Description | Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1. |
| Molecular Formula | C23H45NO10 |
|---|---|
| Molecular Weight | 495.60 |
| Storage condition | 2-8°C |