616884-66-3

616884-66-3 structure

Name: OMDM-5
Chemical Name: OMDM-5
CAS Number: 616884-66-3
Molecular Formula: C₂₆H₄₄N₂O₃
Molecular Weight: 432.64
Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
Create Date: 2020-06-01 10:13:12
Modify Date: 2024-01-30 18:10:09
OMDM-5 is a selective inhibitor of anandamide cellular uptake (ACU), with a Ki of 4.8 μM. OMDM-5 is also a potent vanilloid receptor type 1 (VR1, TRPV1) agonist, with an EC50 of 75 nM, and shows weakly active as cannabinoid receptor type 1 (CB1) ligand (Ki=4.9 μM)[1].

Name	OMDM-5

Description	OMDM-5 is a selective inhibitor of anandamide cellular uptake (ACU), with a Ki of 4.8 μM. OMDM-5 is also a potent vanilloid receptor type 1 (VR1, TRPV1) agonist, with an EC50 of 75 nM, and shows weakly active as cannabinoid receptor type 1 (CB1) ligand (Ki=4.9 μM)[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Neurological Disease
Target	Ki: 4.8 μM (anandamide cellular uptake), 4.9 μM (CB1), EC50: 75 nM (VR1)[1]
References	[1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

Molecular Formula	C₂₆H₄₄N₂O₃
Molecular Weight	432.64