1449390-67-3

1449390-67-3 structure
1449390-67-3 structure
  • Name: Thiol-PEG5-acid
  • Chemical Name: Thiol-PEG5-acid
  • CAS Number: 1449390-67-3
  • Molecular Formula: C13H26O7S
  • Molecular Weight: 326.41
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:24:36
  • Modify Date: 2024-01-10 18:38:42
  • Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Thiol-PEG5-acid
Description Thiol-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C13H26O7S
Molecular Weight 326.41