2421117-98-6
2421117-98-6 structure
- Name: BC-DXI-843
- Chemical Name: N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-Nα-[(4-methylphenyl)sulfonyl]-L-tryptophanamide
- CAS Number: 2421117-98-6
- Molecular Formula: C28H26N4O4S2
- Molecular Weight: 546.660
- Create Date: 2021-01-06 22:28:59
- Modify Date: 2024-04-05 12:33:07
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BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with an IC50 of 0.92 μM, more than 100-fold selectivity over AIMP2 (IC50 >100 μM) in a luciferase assay. BC-DXI-843 acts as a promising lead targeting AIMP2-DX2 in lung cancer.
| Name | N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-Nα-[(4-methylphenyl)sulfonyl]-L-tryptophanamide |
|---|---|
| Synonyms |
N-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-Nα-[(4-methylphenyl)sulfonyl]-L-tryptophanamide
1H-Indole-3-propanamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-α-[[(4-methylphenyl)sulfonyl]amino]-, (αS)- |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H26N4O4S2 |
| Molecular Weight | 546.660 |
| Exact Mass | 546.139526 |
| LogP | 5.89 |
| Index of Refraction | 1.679 |