Shanghai Nianxing Industrial Co., Ltd
China
Product Name: pyridin-d4-4-amine
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Purity: 95.0%
Stocking Period: 10 Day
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26257-21-6

26257-21-6 structure

26257-21-6 structure

Name: 4-Aminopyridine-d4
Chemical Name: pyridin-d4-4-amine
CAS Number: 26257-21-6
Molecular Formula: C₅H₂D₄N₂
Molecular Weight: 98.14
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2022-01-14 18:02:16
Modify Date: 2024-01-13 18:21:42
4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.

Name	pyridin-d4-4-amine

Description	4-Aminopyridine-d4 is deuterium labeled 4-Aminopyridine. 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
Related Catalog	Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Sherratt, R.M., H. Bostock, and T.A. Sears, Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres. Nature, 1980. 283(5747): p. 570-2. [3]. Bouchard, R. and D. Fedida, Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5. J Pharmacol Exp Ther, 1995. 275(2): p. 864-76.

Molecular Formula	C₅H₂D₄N₂
Molecular Weight	98.14