1535963-91-7

1535963-91-7 structure
1535963-91-7 structure
  • Name: Satralizumab
  • Chemical Name: Satralizumab
  • CAS Number: 1535963-91-7
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
  • Create Date: 2022-08-21 17:40:16
  • Modify Date: 2024-01-14 12:42:35
  • Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].

Name Satralizumab
Description Satralizumab, a humanized monoclonal antibody, is a potent Interleukine-6 (IL-6) inhibitor. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research[1][2].
Related Catalog
Target

IL-6

In Vivo Satralizumab (120 mg, Subcutaneously, once every 2 weeks, for 4 weeks) prevents dTAA formation and progression in rattus norvegicus[1]. Animal Model: Rattus norvegicus (forty, male, 10-week-old, four equal groups)[1] Dosage: 120 mg Administration: Subcutaneously, once every 2 weeks, for 4 weeks Result: Prevented dTAA (descending thoracic aorta aneurysm) formation and progression.
References

[1]. Heydari AH, et al. Satralizumab, Novel Interleukine-6 Inhibitor for Preventing Descending Thoracic Aorta Aneurysm Development. Cardiovasc Drugs Ther. 2021 Nov 26.

[2]. Duchow A, et al. Satralizumab in the treatment of neuromyelitis optica spectrum disorder. Neurodegener Dis Manag. 2021 Feb;11(1):49-59.

No Any Chemical & Physical Properties