1178862-65-1

1178862-65-1 structure

Name: Ponezumab
Chemical Name: Ponezumab
CAS Number: 1178862-65-1
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-10-12 18:06:52
Modify Date: 2024-04-08 11:33:01
Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease[1].

Name	Ponezumab

Description	Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Research Areas >> Neurological Disease
Target	IgG2[1].
References	[1]. Nicholas T, et al. Preliminary population pharmacokinetic modeling of PF-04360365, a humanized anti-amyloid monoclonal antibody, in patients with mild-to-moderate Alzheimer's disease[J]. Alzheimer's and Dementia, 2009, 5(4): P253.

No Any Chemical & Physical Properties