2772700-36-2

2772700-36-2 structure

Name: β2AR agonist /M-receptor antagonist-1
Chemical Name: β2AR agonist /M-receptor antagonist-1
CAS Number: 2772700-36-2
Molecular Formula: C₃₃H₄₀FN₅O₅S₂
Molecular Weight: 669.83
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2023-01-14 14:51:47
Modify Date: 2024-01-27 09:26:27
β2AR agonist /M-receptor antagonist-1 is a potent dual muscarinic antagonist/beta 2 agonist (MABA). β2AR agonist /M-receptor antagonist-1 potently relaxes either Carbachol (HY-B1208)-induced contraction, in the absence (MABA) or presence of Propranolol (M3; HY-B1208), or Histamine (HY-B1204)-induced contraction (β2)[1][2].

Name	β2AR agonist /M-receptor antagonist-1

Description	β2AR agonist /M-receptor antagonist-1 is a potent dual muscarinic antagonist/beta 2 agonist (MABA). β2AR agonist /M-receptor antagonist-1 potently relaxes either Carbachol (HY-B1208)-induced contraction, in the absence (MABA) or presence of Propranolol (M3; HY-B1208), or Histamine (HY-B1204)-induced contraction (β2)[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
Target	Beta-2 adrenergic receptor
References	[1]. Huihui Ti, et al. Targeted Treatments for Chronic Obstructive Pulmonary Disease (COPD) Using Low-Molecular-Weight Drugs (LMWDs). J Med Chem. 2019 Jul 11;62(13):5944-5978. [2]. Fiorella Pastore, et al.In vitro pharmacological characterization of the novel inhaled bronchodilator CHF6366 acting as dual muscarinic antagonist/β2-agonist (MABA). European Respiratory Journal 2017 50: PA1805.

Molecular Formula	C₃₃H₄₀FN₅O₅S₂
Molecular Weight	669.83