2102543-86-0

2102543-86-0 structure
2102543-86-0 structure
  • Name: Imsidolimab
  • Chemical Name: Imsidolimab
  • CAS Number: 2102543-86-0
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
  • Create Date: 2023-03-10 17:43:20
  • Modify Date: 2024-04-06 10:53:16
  • Imsidolimab (ANB 019) is a high-affinity, humanized monoclonal antibody of anti-IL-36R. Imsidolimab antagonizes IL-36 cytokine signal transduction. Imsidolimab has potential application in generalized pustular psoriasis (GPP) and other inflammatory skin diseases[1][2].

Name Imsidolimab
Description Imsidolimab (ANB 019) is a high-affinity, humanized monoclonal antibody of anti-IL-36R. Imsidolimab antagonizes IL-36 cytokine signal transduction. Imsidolimab has potential application in generalized pustular psoriasis (GPP) and other inflammatory skin diseases[1][2].
Related Catalog
Target

IL-36R[1]

References

[1]. Gudjonsson J E, et al. 34617 Imsidolimab in the treatment of adult subjects with generalized pustular psoriasis: Design of a pivotal phase 3 clinical trial and a long-term extension study[J]. Journal of the American Academy of Dermatology, 2022, 87(3): AB70.

[2]. Iznardo H, et al. Exploring the Role of IL-36 Cytokines as a New Target in Psoriatic Disease. Int J Mol Sci. 2021 Apr 21;22(9):4344.  

No Any Chemical & Physical Properties