179479-04-0

179479-04-0 structure

Name: 3’-O-Me-G(iBu)-2’-phosphoramidite
Chemical Name: 3’-O-Me-G(iBu)-2’-phosphoramidite
CAS Number: 179479-04-0
Molecular Formula: C₄₄H₅₄N₇O₉P
Molecular Weight: 855.91
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2023-06-15 18:20:39
Modify Date: 2024-09-17 16:44:32
3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	3’-O-Me-G(iBu)-2’-phosphoramidite

Description	3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

Molecular Formula	C₄₄H₅₄N₇O₉P
Molecular Weight	855.91