2905312-07-2

2905312-07-2 structure

2905312-07-2 structure

Name: ATR-IN-22
Chemical Name: ATR-IN-22
CAS Number: 2905312-07-2
Molecular Formula: C₂₅H₃₁N₇O
Molecular Weight: 445.56
Catalog: Signaling Pathways Cell Cycle/DNA Damage ATM/ATR
Create Date: 2023-11-04 09:01:45
Modify Date: 2024-01-03 07:32:16
ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer[1].

Name	ATR-IN-22

Description	ATR-IN-22 (Compound 34) is an orally active ATR inhibitor. ATR-IN-22 inhibits MIAPaCa-2 proliferation (IC50 <1 μM). ATR-IN-22 shows anti-tumor activity in colon cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR
References	[1]. Xie, Yuli, et al. Naphthyridine derivative as ATR inhibitor and method for preparing same. Patent. WO2023016529. 2023-02-16.

Molecular Formula	C₂₅H₃₁N₇O
Molecular Weight	445.56