2757469-20-6

2757469-20-6 structure

Name: Immuno modulator-1
Chemical Name: Immuno modulator-1
CAS Number: 2757469-20-6
Molecular Formula: C₃₂H₃₁FN₆O₄
Molecular Weight: 582.62
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2023-09-24 17:48:03
Modify Date: 2024-01-29 16:45:32
Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].

Name	Immuno modulator-1

Description	Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IL-2
References	[1]. Chen Xiangyang, et al. Heterocyclic immunomodulator. Patent, WO2022007659A1.

Molecular Formula	C₃₂H₃₁FN₆O₄
Molecular Weight	582.62